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CD Proteins
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=== Human CD cellular antigens === </div><div><div> {| border="1" cellspacing="0" cellpadding="1" |- ! Antigen<br/>name ! Other<br/>names ! MW ! Structure ! Distribution ! Function |- | <a title="CD1a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD1a https://www.thermofisher.com/antibody/primary/target/CD1a]">CD1a</a> | T6 | 49kD | IgSF, MHC-like | cortical thymocytes, Langerhans cells, DC | antigen presentation, with beta2m |- | <a title="CD1b Products" href="[https://www.thermofisher.com/antibody/primary/target/CD1b https://www.thermofisher.com/antibody/primary/target/CD1b]">CD1b</a> | T6 | 45kD | IgSF, MHC-like | cortical thymocytes, Langerhans cells, DC | antigen presentation, with beta2m |- | <a title="CD1c Products" href="[https://www.thermofisher.com/antibody/primary/target/CD1c https://www.thermofisher.com/antibody/primary/target/CD1c]">CD1c</a> | T6 | 43kD | IgSF, MHC-like | cortical thymocytes, Langerhans cells, DC, B subset | antigen presentation, with beta2m |- | <a title="CD1d Products" href="[https://www.thermofisher.com/antibody/primary/target/CD1d https://www.thermofisher.com/antibody/primary/target/CD1d]">CD1d</a> | 49kD | IgSF, MHC-like | intestinal epith, B subset, mono<sup>low</sup>, DC | antigen presentation, with beta2m |- | CD1e | 28kD | IgSF, MHC-like | DC | antigen presentation, with beta2m |- | <a title="CD2" href="[https://www.thermofisher.com/antibody/primary/target/CD2 https://www.thermofisher.com/antibody/primary/target/CD2]">CD2</a> | T11, LFA-2, SRBC-R | 50kD | IgSF | thymocytes, T, NK | CD58 ligand, adhesion, T cell activation |- | CD2R | T11-3 | 50kD | IgSF | T<sup>act</sup> | activation-dependent form of CD2 |- | <a title="CD3 Gamma and Delta Products" href="[https://www.thermofisher.com/antibody/primary/target/CD3 https://www.thermofisher.com/antibody/primary/target/CD3]">CD3 gamma, CD3 delta</a> | T3 | IgSF | T, thymocyte subset | with TCR, TCR surface expression / signal transduction |- | <a title="CD3e Products" href="[https://www.thermofisher.com/antibody/primary/target/CD3e https://www.thermofisher.com/antibody/primary/target/CD3e]">CD3 epsilon</a> | T3 | 20kD | IgSF | T, thymocyte subset | with TCR, TCR surface expression / signal transduction |- | <a title="CD4 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD4 https://www.thermofisher.com/antibody/primary/target/CD4]">CD4</a> | T4 | 55kD | IgSF | thymocyte subset, T subset, mono, mac | MHC class II coreceptor, HIV receptor, T cell differentiation / activation |- | <a title="CD5 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD5 https://www.thermofisher.com/antibody/primary/target/CD5]">CD5</a> | T1, Tp67 | 67kD | Scavenger R SF | thymocytes, T, B subset, B-CLL | CD72 receptor, TCR or BCR signaling, T-B interaction |- | <a title="CD6 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD6 https://www.thermofisher.com/antibody/primary/target/CD6]">CD6</a> | T12 | 100-130kD | Scavenger R SF | thymocytes, T, B subset | CD166 receptor, T cell differentiation / costimulation |- | <a title="CD7 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD7 https://www.thermofisher.com/antibody/primary/target/CD7]">CD7</a> | 40kD | IgSF | hematopoietic progenitors, thymocytes, T, NK | T costimulation |- | <a title="CD8a" href="[https://www.thermofisher.com/antibody/primary/target/CD8 https://www.thermofisher.com/antibody/primary/target/CD8]">CD8a</a> | T8, Leu-2 | 32-34kD | IgSF | thymocyte subset, T subset, NK | MHC class I coreceptor, receptor for some mutated HIV-1, T cell differentiation / activation |- | <a title="CD8b" href="[https://www.thermofisher.com/antibody/primary/target/CD8%20beta https://www.thermofisher.com/antibody/primary/target/CD8%20beta]">CD8b</a> | 30-32kD | IgSF | thymocyte subset, T subset |- | <a title="CD9 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD9 https://www.thermofisher.com/antibody/primary/target/CD9]">CD9</a> | p24, MRP-1 | 22-27kD | TM4SF | pre-B, eosinophils, basophils, platelets, T<sup>act</sup> | cellular adhesion and migration |- | <a title="CD10 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD10 https://www.thermofisher.com/antibody/primary/target/CD10]">CD10</a> | CALLA, NEP, gp100 | 100kD | type II TM | B precursors, T precursors, neutrophils | zinc-binding metalloproteinase, B cell development |- | <a title="CD11a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD11a https://www.thermofisher.com/antibody/primary/target/CD11a]">CD11a</a> | LFA-1, integrin alphaL | 180kD | Integrin family | lymph, gran, mono, mac | CD11a / CD18 receptor for ICAM-1, -2,-3, intercellular adhesion, T costimulation |- | <a title="CD11b Products" href="[https://www.thermofisher.com/antibody/primary/target/CD11b https://www.thermofisher.com/antibody/primary/target/CD11b]">CD11b</a> | Mac-1, integrin alphaM | 170kD | Integrin family | myeloid cells, NK | binds CD54, ECM, iC3b |- | <a title="CD11c Products" href="[https://www.thermofisher.com/antibody/primary/target/CD11c https://www.thermofisher.com/antibody/primary/target/CD11c]">CD11c</a> | p150, 95, CR4, integrin alphaX | 150kD | Integrin family | DC, myeloid cells, NK, B, T subset | binds CD54, fibrinogen and iC3b |- | CD12 | 90-120kD | mono, gran, platelets |- | <a title="CD13 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD13 https://www.thermofisher.com/antibody/primary/target/CD13]">CD13</a> | Aminopeptidase N, APN | 150-170kD | type II TM | myeloid cells | zinc-binding metalloproteinase, antigen processing, receptor for corona virus strains |- | <a title="CD14 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD14 https://www.thermofisher.com/antibody/primary/target/CD14]">CD14</a> | LPS-R | 53-55kD | GPI-linked | mono, mac, Langerhans cells, gran<sup>low</sup> | receptor for LPS/LBP, LPS recognition |- | <a title="CD15 Products" href="[https://www.thermofisher.com/antibody/primary/target/SSEA1 https://www.thermofisher.com/antibody/primary/target/SSEA1]">CD15</a> | Lewis-x, Lex | CHO | neutrophils, eosinophils, mono | adhesion |- | CD15s | Sialyl Lewis X | CHO | neutrophils, eosinophils, mono, memory helper T, T<sup>act</sup> and B, NK, HEV | CD62L and CD62P ligand, adhesion |- | CD15u | Sulfated Lewis X | CHO | myeloid subset | adhesion |- | <a title="CD16 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD16 https://www.thermofisher.com/antibody/primary/target/CD16]">CD16a</a> | FcgammaRIIIA | 50-65kD | IgSF | neutrophils, mac, NK | component of low affinity Fc receptor, phagocytosis and ADCC |- | <a title="CD16 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD16 https://www.thermofisher.com/antibody/primary/target/CD16]">CD16b</a> | FcgammaRIIIB | 48kD | IgSF | neutrophils | component of low affinity Fc receptor, phagocytosis and ADCC |- | CD17 | neutrophils, mono, platelets | lactosyl ceramide |- | <a title="CD18 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD18 https://www.thermofisher.com/antibody/primary/target/CD18]">CD18</a> | Integrin beta2 | 95kD | Integrin family | broad, all leukocytes | with CD11a, b & c, adhesion |- | <a title="CD19 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD19 https://www.thermofisher.com/antibody/primary/target/CD19]">CD19</a> | B4 | 95kD | IgSF | B, FDC | complex with CD21 and CD81, BCR coreceptor, B cell activation / differentiation |- | <a title="CD20 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD20 https://www.thermofisher.com/antibody/primary/target/CD20]">CD20</a> | B1, Bp35 | 33-37kD | TM4SF | B, T subset | B cell activation |- | <a title="CD21 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD21 https://www.thermofisher.com/antibody/primary/target/CD21]">CD21</a> | C3DR, CR2, EBV-R | 145,110kD | CCRSF | B, FDC, T subset | complement C3d and EBV receptor, complex with CD19 and CD81, BCR coreceptor |- | <a title="CD22 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD22 https://www.thermofisher.com/antibody/primary/target/CD22]">CD22</a> | BL-CAM, Siglec-2 | 150kD | IgSF, sialoadhesins | B | adhesion, B-mono, B-T interactions |- | <a title="CD23 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD23 https://www.thermofisher.com/antibody/primary/target/CD23]">CD23</a> | FcepsilonRII | 45kD | C-type lectin | B, activated mac, eosinophils, FDC, platelets | CD19-CD21-CD81 receptor, IgE low affinity receptor, signal transduction |- | <a title="CD24 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD24 https://www.thermofisher.com/antibody/primary/target/CD24]">CD24</a> | BA-1 | 35-45kD | GPI-linked | thymocytes, erythrocytes, peripheral lymph, myeloid | binds P-selectin |- | <a title="CD25 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD25 https://www.thermofisher.com/antibody/primary/target/CD25]">CD25</a> | Tac, p55 | 55kD | type I TM | Tact, B<sup>act</sup>, lymph progenitors | IL-2Ralpha, with IL-2Rbeta and gamma to form high affinity complex |- | <a title="CD26 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD26 https://www.thermofisher.com/antibody/primary/target/CD26]">CD26</a> | DPP IV | 110kD | type II TM | thymocyte subset, Tact, soluble form | dipeptidyl peptidase, T costimulation, HIV entry |- | <a title="CD27 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD27 https://www.thermofisher.com/antibody/primary/target/CD27]">CD27</a> | T14 | 50-55kD | TNFRSF | medullary thymocytes, T, B subset, NK subset | CD70 receptor, T costimulation |- | <a title="CD28 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD28 https://www.thermofisher.com/antibody/primary/target/CD28]">CD28</a> | Tp44, T44 | 44kD | IgSF | most T, thymocytes, plasma cells | CD80, CD86 receptor, T costimulation |- | <a title="CD29 Products" href="[https://www.thermofisher.com/antibody/primary/target/ITGB1 https://www.thermofisher.com/antibody/primary/target/ITGB1]">CD29</a> | Integrin beta1 | 130kD | Integrin family | lymph, mono, gran<sup>low</sup>, platelets, mast cells, fibroblasts, endoth | with CD49a (VLA-1) receptor for VCAM-1, MAdCAM-1 and ECM |- | <a title="CD30 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD30 https://www.thermofisher.com/antibody/primary/target/CD30]">CD30</a> | Ki-1 | 105-120kD | TNFRSF | B<sup>act</sup>, T and NK , Reed-Sternberg cells, anaplastic large cell lymphoma | CD153 receptor, lymph proliferation / apoptosis |- | <a title="CD31 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD31 https://www.thermofisher.com/antibody/primary/target/CD31]">CD31</a> | PECAM-1 | 130-140kD | IgSF | mono, platelets, gran, endoth, lymph subset | CD38 receptor, adhesion |- | <a title="CD32 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD32 https://www.thermofisher.com/antibody/primary/target/CD32]">CD32</a> | FcgammaRII | 40kD | IgSF | mono, gran, B, platelets | low affinity Fc receptor for aggregated Ig and immune complexes |- | <a title="CD33 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD33 https://www.thermofisher.com/antibody/primary/target/CD33]">CD33</a> | p67, Siglec-3 | 67kD | IgSF, sialoadhesins | myeloid progenitors, mono, gran, DC, mast cells, Tact | adhesion |- | <a title="CD34 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD34 https://www.thermofisher.com/antibody/primary/target/CD34]">CD34</a> | 105-120kD | Sialomucin, type I TM | hematopoietic precursors, capillary endoth, embryonic fibroblasts | stem cell marker, adhesion, CD62L receptor |- | CD35 | CR1 | 250kD | CCRSF | erythrocytes, B, mono, neutrophils, eosinophils, FDC, T subset | complement receptor 1, binds C3b and C4b, adhesion, phagocytosis |- | <a title="CD36 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD36 https://www.thermofisher.com/antibody/primary/target/CD36]">CD36</a> | GPIV | 88kD | platelets, mono, mac, endoth, early erythrocytes | ECM receptor, adhesion, phagocytosis |- | CD37 | 40-52kD | TM4SF | B, T<sup>low</sup>, gran<sup>low</sup> | signal transduction |- | <a title="CD38 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD38 https://www.thermofisher.com/antibody/primary/target/CD38]">CD38</a> | T10 | 45kD | variable levels on majority of hematopoietic cells, high expression on plasma cells, B and Tact | ecto-ADP-ribosyl cyclase, cell activation |- | <a title="CD39 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD39 https://www.thermofisher.com/antibody/primary/target/CD39]">CD39</a> | 78kD | NK, mac, Langerhans cells, DC, B<sup>act</sup> | B cell adhesion, protects activated cells from lysis, ecto-apyrase |- | <a title="CD40 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD40 https://www.thermofisher.com/antibody/primary/target/CD40]">CD40</a> | 48kD | TNFRSF | B, mono, mac, FDC, endoth, T subset | CD154 receptor, B differentiation / costimulation, isotype-switching, rescues B cells from apoptosis |- | <a title="CD41 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD41 https://www.thermofisher.com/antibody/primary/target/CD41]">CD41</a> | gpIIb | 125/22kD | Integrin family | platelets, megakaryocytes | with CD61 forms GPIIb, binds fibrinogen, fibronectin, vWF, thrombospondin, platelet activation and aggregation |- | <a title="CD42a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD42a https://www.thermofisher.com/antibody/primary/target/CD42a]">CD42a</a> | GPIX | 22kD | LRRF | platelets, megakaryocytes | complex with CD42b, c and d, receptor for vWF and thrombin, platelet adhesion to subendothelial matrices |- | <a title="CD42b" href="[https://www.thermofisher.com/antibody/primary/target/CD42b https://www.thermofisher.com/antibody/primary/target/CD42b]">CD42b</a> | GPIba | 145kD | LRRF | platelets, megakaryocytes | complex with CD42a, c and d, binds to vWF and thrombin, platelet adhesion / activation |- | CD42c | GPIbb | 24kD | LRRF | platelets, megakaryocytes | complex with CD42a, b, d |- | <a title="CD42d Products" href="[https://www.thermofisher.com/antibody/primary/target/GP5 https://www.thermofisher.com/antibody/primary/target/GP5]">CD42d</a> | GPV | 82kD | LRRF | platelets, megakaryocytes | complex with CD42a-c |- | <a title="CD43" href="[https://www.thermofisher.com/antibody/primary/target/CD43 https://www.thermofisher.com/antibody/primary/target/CD43]">CD43</a> | Leukosialin, sialophorin | 115-135kD | Sialomucin, type I TM | leukocytes, except resting B, platelets<sup>low</sup> | inhibition of T cell interaction, CD54R, adhesion |- | <a title="CD44 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD44 https://www.thermofisher.com/antibody/primary/target/CD44]">CD44</a> | H-CAM, Pgp-1 | 80-95kD | hyaladherin family | hematopoietic and non-hematopoietic cells, except platelets, hepatocytes, testis | binds hyaluronic acid, adhesion |- | CD44v | CD44 variants heterogeneous expression, constitutively on epith, mono, upregulated on activated leukocytes | adhesion, metastasis |- | <a title="CD45 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD45m https://www.thermofisher.com/antibody/primary/target/CD45m]">CD45</a> | LCA, T200, B220 | 180-240kD | hematopoietic cells, multiple isoforms from alternative splicing | tyrosine phosphatase, enhanced TCR & BCR signals |- | <a title="CD45RA Products" href="[https://www.thermofisher.com/antibody/primary/target/CD45RA https://www.thermofisher.com/antibody/primary/target/CD45RA]">CD45RA</a> | 205-220kD | B, T subset(naive), mono | exon A isoforms of CD45 |- | <a title="CD45RB Products" href="[https://www.thermofisher.com/antibody/primary/target/CD45RB https://www.thermofisher.com/antibody/primary/target/CD45RB]">CD45RB</a> | 190-220kD | T subset, B, mono, mac, gran | exon B isoforms of CD45 |- | <a title="CD45RO Products" href="[https://www.thermofisher.com/antibody/primary/target/CD45RO https://www.thermofisher.com/antibody/primary/target/CD45RO]">CD45RO</a> | 180kD | Tact, memory T, B subset, mono, mac, gran | isoform of CD45 lacking A, B, C exons |- | <a title="CD46 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD46 https://www.thermofisher.com/antibody/primary/target/CD46]">CD46</a> | MCP | 56/66kD | CCRSF | nucleated cells | membrane cofactor protein, binds C3b & C4b allowing degradation by Factor I, measles virus receptor |- | <a title="CD47 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD47 https://www.thermofisher.com/antibody/primary/target/CD47]">CD47</a> | IAP | 47-52kD | IgSF | hematopoietic cells, epith, endoth, fibroblasts, other tissues | leukocyte adhesion, migration, activation |- | CD47R | New designation for CDw149, similar distribution as CD47 but dimmer |- | <a title="CD48 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD48 https://www.thermofisher.com/antibody/primary/target/CD48]">CD48</a> | Blast-1 | 45kD | IgSF | broad, all leukocytes | cell adhesion |- | CD49a | VLA-1 | 210kD | Integrin family | Tact, mono | integrin alpha1, adhesion, CD49a/CD29 binds collagen and laminin |- | <a title="CD49b Products" href="[https://www.thermofisher.com/antibody/primary/target/CD41 https://www.thermofisher.com/antibody/primary/target/CD41]">CD49b</a> | VLA-2 | 165kD | Integrin family | B, mono, platelets, Tact, megakaryocytes | integrin alpha2, adhesion, CD49b / CD29 binds collagen and laminin |- | <a title="CD49c Products" href="[https://www.thermofisher.com/antibody/primary/target/ITGA3 https://www.thermofisher.com/antibody/primary/target/ITGA3]">CD49c</a> | VLA-3 | 125kD | Integrin family | B and T<sup>low</sup>, most adhesive cell lines | integrin alpha3, adhesion, CD49c/CD29 binds laminin, fibronectin and collagen |- | <a title="CD49d Products" href="[https://www.thermofisher.com/antibody/primary/target/ITGA4 https://www.thermofisher.com/antibody/primary/target/ITGA4]">CD49d</a> | VLA-4 | 150kD | Integrin family | T, B, NK, thymocytes, mono, eosinophils, mast, DC | integrin alpha4, adhesion, CD49d/CD29 binds fibronectin, VCAM-1 & MAdCAM-1 |- | <a title="CD49e Products" href="[https://www.thermofisher.com/antibody/primary/target/ITGA5 https://www.thermofisher.com/antibody/primary/target/ITGA5]">CD49e</a> | VLA-5 | 135, 25kD | Integrin family | thymocytes, T, mono, platelets, early and B<sup>act</sup> | integrin alpha5, adhesion, CD49e/CD29 binds fibronectin |- | <a title="CD49f Products" href="[https://www.thermofisher.com/antibody/primary/target/CD49f https://www.thermofisher.com/antibody/primary/target/CD49f]">CD49f</a> | VLA-6 | 125kD | Integrin family | memory T, thymocytes, mono, platelets, megakaryocytes, epith | integrin alpha6, adhesion, CD49f / CD29 binds laminin |- | <a title="CD50 Products" href="[https://www.thermofisher.com/antibody/primary/target/ICAM-3 https://www.thermofisher.com/antibody/primary/target/ICAM-3]">CD50</a> | ICAM-3 | 110-120kD | IgSF | hematopoietic, endoth, epidermal Langerhans cells | adhesion, costimulation |- | <a title="CD51 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD51 https://www.thermofisher.com/antibody/primary/target/CD51]">CD51</a> | Vitronectin receptor | 125, 24kD | Integrin family | platelets<sup>low</sup>, endoth, osteoblasts, melanomas | integrin alphav, adhesion, CD51 / CD61 binds vitronectin, vWF, fibrinogen and thrombospondin |- | CD52 | CAMPATH-1 | 21-28kD | thymocytes, T, B (not plasma cells), mono, mac |- | CD53 | 35-42kD | TM4SF | leukocytes, DC, osteoblasts, osteoclasts | signal transduction |- | <a title="CD54 Products" href="[https://www.thermofisher.com/antibody/primary/target/ICAM-1 https://www.thermofisher.com/antibody/primary/target/ICAM-1]">CD54</a> | ICAM-1 | 90-110kD | IgSF | endoth, mono, lymph (high upon activation) | receptor for CD11a / CD18 (LFA-1), CD11b/CD18 (Mac-1) and rhinovirus |- | <a title="CD55 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD55 https://www.thermofisher.com/antibody/primary/target/CD55]">CD55</a> | DAF | 60-70kD | GPI-linked | hematopoietic, endoth | binds C3b, complement regulation |- | <a title="CD56 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD56 https://www.thermofisher.com/antibody/primary/target/CD56]">CD56</a> | NCAM | 175-185kD | IgSF | NK, T subset, neurons, some large granular lymphocyte leukemias, myeloid leukemias | adhesion |- | <a title="CD57 Products" href="[https://www.thermofisher.com/antibody/primary/target/KLRG1 https://www.thermofisher.com/antibody/primary/target/KLRG1]">CD57</a> | HNK-1, Leu-7 | 110kD | NK subset, T subset |- | <a title="CD58 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD58 https://www.thermofisher.com/antibody/primary/target/CD58]">CD58</a> | LFA-3 | 55-70kD | IgSF | hematopoietic, non-hematopoietic cells | CD2 receptor, adhesion |- | <a title="CD59 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD59 https://www.thermofisher.com/antibody/primary/target/CD59]">CD59</a> | Protectin, MAC- inhibitor | 19kD | GPI-linked | hematopoietic, non-hematopoietic cells | binds complement C8 and C9, blocks assembly of membrane attack complex |- | CD60a | GD3 | CHO | T subset, platelets, thymic epith, astrocytes | costimulation |- | CD60b | 9-O-sialyl GD3 | CHO | T subset, B<sup>act</sup> |- | CD60c | 7-O-sialyl GD3 | CHO | T subset |- | <a title="CD61 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD61 https://www.thermofisher.com/antibody/primary/target/CD61]">CD61</a> | GPIIIa | 105kD | Integrin family | platelets, megakaryocytes, mac, endoth | integrin beta3, adhesion, CD41/CD61 or CD51 / CD61 mediate adhesion to ECM |- | <a title="CD62E Products" href="[https://www.thermofisher.com/antibody/primary/target/E-selectin https://www.thermofisher.com/antibody/primary/target/E-selectin]">CD62E</a> | E-selectin, ELAM-1 | 97,107-115kD | Selectin family | endoth | binds CD15s, cell rolling, metastasis |- | <a title="CD62L" href="[https://www.thermofisher.com/antibody/primary/target/CD62L https://www.thermofisher.com/antibody/primary/target/CD62L]">CD62L</a> | L-selectin, LECAM-1 | 74, 95kD | Selectin family | B, naïve and memory T, mono, gran, NK, thymocytes | CD34, GlyCAM, and MAdCAM-1 receptor, leukocyte homing, tethering, rolling |- | <a title="CD62P Products" href="[https://www.thermofisher.com/antibody/primary/target/P-Selectin https://www.thermofisher.com/antibody/primary/target/P-Selectin]">CD62P</a> | P-selectin, PADGEM | 140kD | Selectin family | activated platelets, endoth | CD162, CD15s receptor, adhesion, neutrophil rolling, platelet-neutrophil and platelet-mono interactions |- | CD63 | LIMP, LAMP-3 | 53kD | TM4SF | activated platelets, mono, mac | lysosomal membrane protein, moves to cell surface after activation |- | <a title="CD64 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD64 https://www.thermofisher.com/antibody/primary/target/CD64]">CD64</a> | FcgammaRI | 72kD | IgSF | mono, mac, DC, Interferon or G-CSF activated gran | high affinity receptor for IgG, phagocytosis and ADCC |- | <a title="CD65 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD65 https://www.thermofisher.com/antibody/primary/target/CD65]">CD65</a> | gran, mono subset, myeloid leukemias |- | CD65s | VIM2 | gran, mono, myeloid leukemias | phagocytosis |- | <a title="CD66a Products" href="[https://www.thermofisher.com/antibody/primary/target/CEACAM1 https://www.thermofisher.com/antibody/primary/target/CEACAM1]">CD66a</a> | BGP-1, NCA-160 | 160-180kD | IgSF, CEA family | neutrophils, epith | cell adhesion |- | CD66b | CD67, CGM6 | 95-100kD | IgSF, CEA family | gran | cell adhesion, neutrophil activation |- | CD66c | NCA | 90kD | IgSF, CEA family | neutrophils, colon carcinoma | cell adhesion |- | CD66d | CGM1 | 35kD | IgSF, CEA family | neutrophils |- | <a title="CD66e Products" href="[https://www.thermofisher.com/antibody/primary/target/CEA https://www.thermofisher.com/antibody/primary/target/CEA]">CD66e</a> | CEA | 180-200kD | IgSF, CEA family | colon epith, colon cancer | cell adhesion |- | CD66f | PSG, Sp-1 | 54-72kD | IgSF, CEA family | pregnancy specific glycoprotein, placental syncytiotrophoblasts, fetal liver | immune regulation, protects fetus from maternal immune system |- | <a title="CD68 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD68 https://www.thermofisher.com/antibody/primary/target/CD68]">CD68</a> | Macrosialin, gp110 | 110kD | Sialomucin | intracellularly in mono, mac, neutrophils, basophils, large lymph, mast cells, DC, myeloid progenitors, liver |- | <a title="CD69 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD69 https://www.thermofisher.com/antibody/primary/target/CD69]">CD69</a> | AIM | 28, 32kD | C-type lectin | Tact, B, NK and gran, thymocytes, platelets, Langerhans cells | signal transduction |- | <a title="CD70 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD70 https://www.thermofisher.com/antibody/primary/target/CD70]">CD70</a> | Ki-24 | 50, 70, 90, 160kD | TNFSF | B<sup>act</sup> and Tact | CD27 ligand, T and B cell costimulation |- | <a title="CD71 Products" href="[https://www.thermofisher.com/antibody/primary/target/Transferrin%20Receptor https://www.thermofisher.com/antibody/primary/target/Transferrin%20Receptor]">CD71</a> | T9 | 95kD | proliferating cells, reticulocytes, erythroid precursors | transferrin receptor, iron uptake |- | CD72 | Lyb-2 | 42kD | C-type lectin | B, FDC | CD5, CD100 receptor, B proliferation |- | <a title="CD73 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD73 https://www.thermofisher.com/antibody/primary/target/CD73]">CD73</a> | 69kD | GPI-linked | B subset, T subset, FDC, epith | ecto-5’-nucleotidase, nucleoside uptake, T costimulation, lymph adhesion |- | <a title="CD74 Products" href="[https://www.thermofisher.com/antibody/primary/target/MHC%20II%20HLA-DR https://www.thermofisher.com/antibody/primary/target/MHC%20II%20HLA-DR]">CD74</a> | Ii, invariant chain | 33, 35, 41, 43kD | B, mac, mono, Langerhans cells, DC, Tact | MHC class II traffic and function |- | CD75 | CHO Sialoglycan family | B subset, epith | lactosamines |- | CD75s | CHO Sialoglycan family | B subset, T subset | alpha-2,6-sialylated lactosamines (previously CDw75 and CDw76) |- | CD77 | Gb3, Pk blood group | germinal center B, Burkitt’s lymphomas<sup>high</sup>, follicular lymphomas<sup>low</sup> | apoptosis |- | <a title="CD79a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD79a https://www.thermofisher.com/antibody/primary/target/CD79a]">CD79a</a> | Iga | 33, 45kD | IgSF | B | component of BCR, BCR surface expression and signal transduction |- | <a title="CD79b Products" href="[https://www.thermofisher.com/antibody/primary/target/CD79b https://www.thermofisher.com/antibody/primary/target/CD79b]">CD79b</a> | Igb | 37kD | IgSF | B | component of BCR, BCR surface expression and signal transduction |- | <a title="CD80 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD80 https://www.thermofisher.com/antibody/primary/target/CD80]">CD80</a> | B7, B7-1, BB1 | 60kD | IgSF | B<sup>act</sup> and Tact, mac, DC | binds to CD28, CD152, T costimulation |- | <a title="CD81 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD81 https://www.thermofisher.com/antibody/primary/target/CD81]">CD81</a> | TAPA-1 | 26kD | TM4SF | T, B, NK, thymocytes, DC, endoth, fibroblast, neuroblastomas, melanomas | complex with CD19 & CD21, signaling, T costimulation |- | <a title="CD82 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD82 https://www.thermofisher.com/antibody/primary/target/CD82]">CD82</a> | R2 | 50-53kD | TM4SF | leukocytes | signal transduction |- | <a title="CD83 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD83 https://www.thermofisher.com/antibody/primary/target/CD83]">CD83</a> | HB15 | 43kD | IgSF | B<sup>act</sup> and Tact, DC, Langerhans cells |- | CDw84 | 73kD | mono, platelets, B, T subset, mac subset |- | CD85 | 110kD | IgSF, ILT/LIR family | DC, mono, B, NK, T subset | inhibition of NK, T cell cytolytic function |- | <a title="CD86 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD86 https://www.thermofisher.com/antibody/primary/target/CD86]">CD86</a> | B70, B7-2 | 80kD | IgSF | mono, DC, B<sup>act</sup> and Tact | binds to CD28, CD152, T costimulation |- | <a title="CD87 Products" href="[https://www.thermofisher.com/antibody/primary/target/uPAR https://www.thermofisher.com/antibody/primary/target/uPAR]">CD87</a> | UPA-R | 39-66kD | GPI-linked | gran, mono, NK, Tact, endoth, fibroblasts | urokinase plasminogen activator receptor, inflammatory cell invasion, metastasis |- | CD88 | C5aR | 40kD | TM7SF | gran, mono, DC | C5a receptor, granulocyte activation |- | CD89 | FcalphaR | 55-75kD | IgSF | mono, mac, gran, neutrophils, B subset, T subset | IgA receptor, phagocytosis, degranulation, respiratory burst |- | <a title="CD90 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD90 https://www.thermofisher.com/antibody/primary/target/CD90]">CD90</a> | Thy-1 | 25-35kD | IgSF, GPI-linked | CD34+ hematopoietic subset, neurons | hematopoietic stem cell and neuron differentiation |- | CD91 | 600kD | LDLR family | mono, mac, neurons, fibroblasts | receptor for alpha-2-macroglobulin |- | CD92 | 70kD | neutrophils, mono, platelets, endoth, fibroblasts |- | <a title="CD93 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD93 https://www.thermofisher.com/antibody/primary/target/CD93]">CD93</a> | 120kD | neutrophils, mono, endoth |- | <a title="CD94 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD94 https://www.thermofisher.com/antibody/primary/target/CD94]">CD94</a> | KP43 | 43kD | C-type lectin | NK, T subset | complex with NKG2, inhibits NK function |- | <a title="CD95 Products" href="[https://www.thermofisher.com/antibody/primary/target/FAS https://www.thermofisher.com/antibody/primary/target/FAS]">CD95</a> | Apo-1, Fas | 45kD | TNFRSF | lymph (high upon activation), mono, neutrophils | FasL (CD178) receptor, apoptosis |- | <a title="CD96 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD96 https://www.thermofisher.com/antibody/primary/target/CD96]">CD96</a> | TACTILE | 160kD | IgSF | NK, Tact | adhesion of activated T and NK |- | <a title="CD97 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD97 https://www.thermofisher.com/antibody/primary/target/CD97]">CD97</a> | 74, 80, 90kD | TM7SF | B<sup>act</sup> and Tact, mono, gran |- | <a title="CD98 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD98 https://www.thermofisher.com/antibody/primary/target/CD98]">CD98</a> | 4F2 | 80, 40kD | T, B, NK, gran, all human cell lines | cellular activation |- | <a title="CD99 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD99 https://www.thermofisher.com/antibody/primary/target/CD99]">CD99</a> | MIC2, E2 | 32kD | leukocytes | T cell activation, adhesion |- | CD99R | E2 | 32kD | T, NK, myeloid cells | isoform of CD99 |- | <a title="CD100 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD100 https://www.thermofisher.com/antibody/primary/target/CD100]">CD100</a> | 150kD | hematopoietic cells except immature bone marrow cells, RBC and platelets | cell adhesion, cellular activation |- | <a title="CD101 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD101 https://www.thermofisher.com/antibody/primary/target/CD101]">CD101</a> | V7, p126 | 120kD | IgSF | mono, gran, DC, Tact | T cell activation |- | <a title="CD102 Products" href="[https://www.thermofisher.com/antibody/primary/target/ICAM-2 https://www.thermofisher.com/antibody/primary/target/ICAM-2]">CD102</a> | ICAM-2 | 55-65kD | IgSF | lymph, mono, platelets, endoth | binds CD11a / CD18, costimulation |- | <a title="CD103 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD103 https://www.thermofisher.com/antibody/primary/target/CD103]">CD103</a> | HML-1, alpha6, integrin alphaE | 150, 25kD | Integrin family | intraepithelial lymph, lymph subset, activated lymph | with integrin beta7, binds E-cadherin, lymph homing/retention |- | <a title="CD104 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD104 https://www.thermofisher.com/antibody/primary/target/CD104]">CD104</a> | beta4 integrin | 220kD | Integrin family | epith, Schwann cells, keratinocytes, some tumor cells | with integrin alpha6 (CD49f), cell adhesion, differentiation, metastasis |- | <a title="CD105 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD105 https://www.thermofisher.com/antibody/primary/target/CD105]">CD105</a> | Endoglin | 95kD | homodimer | endoth, bone marrow subset, activated mac | cellular response to TGF-beta1 |- | <a title="CD106 Products" href="[https://www.thermofisher.com/antibody/primary/target/VCAM-1 https://www.thermofisher.com/antibody/primary/target/VCAM-1]">CD106</a> | VCAM-1 | 110kD | IgSF | activated endoth, FDC | VLA-4 (CD49d / CD29) receptor, leukocyte adhesion, migration, costimulation |- | <a title="CD107a Products" href="[https://www.thermofisher.com/antibody/primary/target/LAMP1 https://www.thermofisher.com/antibody/primary/target/LAMP1]">CD107a</a> | LAMP-1 | 110kD | activated platelets, T, endoth, metastatic tumors | a lysosomal membrane protein |- | <a title="CD107b Products" href="[https://www.thermofisher.com/antibody/primary/target/LAMP2 https://www.thermofisher.com/antibody/primary/target/LAMP2]">CD107b</a> | LAMP-2 | 120kD | activated platelets, T, endoth, metastatic tumors | a lysosomal membrane protein |- | CD108 | 80kD | erythrocytes, lymphoblasts, resting lymph<sup>low</sup> |- | <a title="CD109 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD109 https://www.thermofisher.com/antibody/primary/target/CD109]">CD109</a> | 170kD | Tact and platelets, CD34+ subset, endoth |- | CD110 | MPL, TPO-R | 82-84kD | CRSF | megakaryocytes, platelets, some CD34+ stem cells<sup>low</sup> | thrombopoietin receptor, megakaryocyte progenitor cell growth / differentiation |- | CD111 | PRR1, Nectin-1 | 64-72kD | IgSF | stem cell subset, mac, neutrophils |- | <a title="CD112 Products" href="[https://www.thermofisher.com/antibody/primary/target/Nectin%202 https://www.thermofisher.com/antibody/primary/target/Nectin%202]">CD112</a> | PRR2, Nectin-2 | 64-72kD | IgSF | mono, neutrophils, CD34+ subset, megakaryocytes, endoth, epith | intercellular adhesion |- | CD113 | PVRL3, Nectin3 | 83kD | IgSF | testis, placenta | adhesion molecule that interacts with afadin |- | CD114 | G-CSFR | 95, 139kD | CRSF | myeloid progenitors, endoth | myeloid differentiation / proliferation |- | <a title="CD115 Products" href="[https://www.thermofisher.com/antibody/primary/target/CSF1R https://www.thermofisher.com/antibody/primary/target/CSF1R]">CD115</a> | M-CSFR, c-fms | 150kD | IgSF, RTK family | mono, mac, monocytic progenitors | CSF-1R, monocytic differentiation / proliferation |- | <a title="CD116 Products" href="[https://www.thermofisher.com/antibody/primary/target/CSF2RA https://www.thermofisher.com/antibody/primary/target/CSF2RA]">CD116</a> | GM-CSFRalpha | 70-85kD | CRSF | mono, gran, DC, endoth | with common beta, myeloid differentiation / proliferation |- | <a title="CD117 Products" href="[https://www.thermofisher.com/antibody/primary/target/c-Kit https://www.thermofisher.com/antibody/primary/target/c-Kit]">CD117</a> | c-kit, SCFR | 145kD | IgSF, RTK family | hematopoietic progenitors, mast cells | SCF receptor, hematopoietic progenitor development / differentiation |- | CD118 | LIFR, gp190 | 190kD | Type I CRSF & secreted forms | epithelial cells in adult and embryo | membrane-bound involved in signal transduction, soluble form inhibits activity of LIF |- | <a title="CD119 Products" href="[https://www.thermofisher.com/antibody/primary/target/IFNGR1 https://www.thermofisher.com/antibody/primary/target/IFNGR1]">CD119</a> | IFNgammaR | 90-100kD | mac, mono, B, T, NK, neutrophils, endoth | IFN-gamma Ralpha, with IFN-gamma AF-1, host defense |- | <a title="CD120a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD357 https://www.thermofisher.com/antibody/primary/target/CD357]">CD120a</a> | TNFR-I | 50-60kD | TNFRSF | hematopoietic, non-hematopoietic cells | receptor for both TNF-alpha and TNF-beta |- | <a title="CD120b Products" href="[https://www.thermofisher.com/antibody/primary/target/TNFR2 https://www.thermofisher.com/antibody/primary/target/TNFR2]">CD120b</a> | TNFR-II | 75-85kD | TNFRSF | hematopoietic, non-hematopoietic cells | receptor for both TNF-alpha and TNF-beta |- | CD121a | IL-1R type I | 80kD | IgSF | dimly expressed on many cells | binds IL-1alpha and IL-1beta, IL-1 signaling |- | CD121b | IL-1R, type II | 60-70kD | IgSF | B, mac, mono, T subset | binds IL-1alpha and IL-1beta, negative signals |- | <a title="CD122 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD122 https://www.thermofisher.com/antibody/primary/target/CD122]">CD122</a> | IL-2Rbeta | 75kD | CRSF | NK, T, B, mono | IL-2Rbeta and IL-15Rbeta, signal transduction |- | <a title="CD123 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD123 https://www.thermofisher.com/antibody/primary/target/CD123]">CD123</a> | IL-3R | 70kD | CRSF | lymph subset, basophils, hematopoietic progenitors, mac, DC, megakaryocytes | IL-3Ralpha, with CDw131 |- | <a title="CD124 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL4R https://www.thermofisher.com/antibody/primary/target/IL4R]">CD124</a> | IL-4R | 140kD | CRSF | lymph<sup>low</sup>, mono, hematopoietic precursors, fibroblast, epith | IL-4Ralpha, with CD132 or IL-13Ralpha, T cell growth / differentiation |- | CD125 | IL-5R | 60kD | CRSF | eosinophils, basophils | IL-5Ralpha, with CDw131 |- | <a title="CD126 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL-6%20Receptor https://www.thermofisher.com/antibody/primary/target/IL-6%20Receptor]">CD126</a> | IL-6R | 80kD | IgSF, CRSF | B<sup>act</sup> and plasma cells, most leukocytes<sup>low</sup>, fibroblasts | IL-6Ralpha, with CD130 |- | <a title="CD127 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL7R https://www.thermofisher.com/antibody/primary/target/IL7R]">CD127</a> | IL-7R | 65-75kD | CRSF | T, pro-B | IL-7Ralpha, with CD132, B and T cell development |- | CD128 | see CD181 & CD182 |- | <a title="CD130 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD130 https://www.thermofisher.com/antibody/primary/target/CD130]">CD130</a> | IL-6Rbeta, gp130 | 130kD | CRSF | B<sup>act</sup> and plasma cells, most leukocytes<sup>low</sup>, endoth | IL-6Rbeta, IL-6, IL-11, LIF, CNF signals |- | <a title="CD131 Products" href="[https://www.thermofisher.com/antibody/primary/target/CSF2RB https://www.thermofisher.com/antibody/primary/target/CSF2RB]">CD131</a> | IL-3R common beta | 95-120kD | CRSF | mono, gran, early B | with alpha subunits of IL-3R, IL-5R, and GM-CSFR, signal transduction |- | <a title="CD132 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL2RG https://www.thermofisher.com/antibody/primary/target/IL2RG]">CD132</a> | Common gamma | 64kD | CRSF | T, B, NK, mono, gran | subunit of IL-2R, IL-4R, IL-7R, IL-9R, and IL-15R, signal transduction |- | <a title="CD133 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD133 https://www.thermofisher.com/antibody/primary/target/CD133]">CD133</a> | AC133, prominin-like 1 | 120kD | TM5SF | hematopoietic stem cell subset, epith, endoth |- | <a title="CD134 Products" href="[https://www.thermofisher.com/antibody/primary/target/OX40 https://www.thermofisher.com/antibody/primary/target/OX40]">CD134</a> | OX-40 | 48-50kD | TNFRSF | Tact | T cell activation, differentiation, apoptosis |- | <a title="CD135 Products" href="[https://www.thermofisher.com/antibody/primary/target/FLT3 https://www.thermofisher.com/antibody/primary/target/FLT3]">CD135</a> | Flt3/Flk2 | 130-150kD | RTK family | myelomonocytic, primitive B progenitors | tyrosine kinase, binds FLT3 ligand, early lymph development |- | CD136 | MSP-R, RON | 180kD | RTK family | epith, CNS, PNS, hematopoietic subset | migration, morphological change and proliferation of different target cells |- | <a title="CD137 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD137 https://www.thermofisher.com/antibody/primary/target/CD137]">CD137</a> | 4-1BB | 30kD | TNFRSF | Tact | T costimulation |- | <a title="CD138 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD138 https://www.thermofisher.com/antibody/primary/target/CD138]">CD138</a> | Syndecan-1 | 80-150kD | Syndecan family | plasma cells, pre-B, basolateral surface of epith, neurons | receptor for ECM, cell morphology |- | CD139 | 228kD | B, mono, gran, erythrocytes<sup>low</sup> |- | <a title="CD140a Products" href="[https://www.thermofisher.com/antibody/primary/target/PDGFRA https://www.thermofisher.com/antibody/primary/target/PDGFRA]">CD140a</a> | PDGFRalpha | 180kD | RTK family | fibroblasts, smooth muscle & glial cells, chondrocytes | binds PDGF A and B |- | <a title="CD140b Products" href="[https://www.thermofisher.com/antibody/primary/target/PDGFRB https://www.thermofisher.com/antibody/primary/target/PDGFRB]">CD140b</a> | PDGFRbeta | 180kD | RTK family | fibroblasts, smooth muscle & glial cells, chondrocytes | binds PDGF B |- | CD141 | Thrombomodulin | 100kD | C-type lectin | mono, neutrophils, endoth, smooth muscle cells | initiation of protein C anticoagulant signal |- | CD142 | Tissue Factor | 45kD | mono, endoth, keratinocytes, epith | binds clotting factor VIIa, initiator of clotting |- | CD143 | ACE | 170kD | endoth, epith, neurons, fibroblasts, activated mac | angiotensin converting enzyme, angiotensin II & bradykinin metabolism |- | <a title="CD144 Products" href="[https://www.thermofisher.com/antibody/primary/target/VE-cadherin https://www.thermofisher.com/antibody/primary/target/VE-cadherin]">CD144</a> | VE-Cadherin, Cadherin-5 | 130kD | Cadherin family | endoth | adhesion, cell-cell interaction |- | CD145 | 110, 90kD | endoth, some stromal cells |- | <a title="CD146 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD146 https://www.thermofisher.com/antibody/primary/target/CD146]">CD146</a> | MUC18, S-endo | 113-118kD | IgSF | endoth, melanomas, FDC, Tact | adhesion |- | <a title="CD147 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD147 https://www.thermofisher.com/antibody/primary/target/CD147]">CD147</a> | Neurothelin, basoglin | IgSF | leukocytes, erythrocytes, platelets, endoth | adhesion |- | <a title="CD148 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD148 https://www.thermofisher.com/antibody/primary/target/CD148]">CD148</a> | HPTP-eta | 240-260kD | gran, mono, DC, T (high upon activation) | tyrosine phosphatase R Type III |- | <a title="CD150 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD150 https://www.thermofisher.com/antibody/primary/target/CD150]">CD150</a> | SLAM | 75-95kD | IgSF | T subset (high upon activation), B, DC, endoth | costimulation, proliferation, Ig production, measles virus receptor |- | <a title="CD151 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD151 https://www.thermofisher.com/antibody/primary/target/CD151]">CD151</a> | PETA-3 | 32kD | endoth, megakaryocytes, platelets, epith | cell adhesion |- | <a title="CD152 Products" href="[https://www.thermofisher.com/antibody/primary/target/CTLA-4 https://www.thermofisher.com/antibody/primary/target/CTLA-4]">CD152</a> | CTLA-4 | 33kD | IgSF | Tact and B | CD80 and CD86 receptor, negative regulation of T cell costimulation |- | <a title="CD153 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD153 https://www.thermofisher.com/antibody/primary/target/CD153]">CD153</a> | CD30L | 40kD | TNFSF | neutrophils, B, Tact and mac | CD30 ligand, T costimulation |- | <a title="CD154 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD40LG https://www.thermofisher.com/antibody/primary/target/CD40LG]">CD154</a> | CD40L, gp39, TRAP | 32-39kD | TNFSF | Tact | CD40 ligand, B and DC costimulation |- | <a title="CD155 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD155 https://www.thermofisher.com/antibody/primary/target/CD155]">CD155</a> | PVR | 80-90kD | IgSF | mono, mac, CD34+ thymocytes | Polio virus receptor (PVR) |- | CD156a | ADAM8 | 69kD | neutrophils, mono | leukocyte extravasation |- | CD156b | TACE / ADAM 17 | 100kD | broad | cleaves membrane proteins (TNF, TGFalpha) to generate soluble forms |- | CD156c | ADAM10 | 98kD | Peptidase M12B family | lymphoid organs, peripheral blood leukocyte, cartilage, chondrocytes and fetal liver | proteolytic cleavage of cell-surface molecules including Notch, TNF-alpha, APP and ephrin-A2 |- | <a title="CD157 Products" href="[https://www.thermofisher.com/antibody/primary/target/CST1 https://www.thermofisher.com/antibody/primary/target/CST1]">CD157</a> | BST-1 | 42-45kD | gran, mono, B progenitors, endoth | ADP-ribosyl-cyclic ADP-ribose hydrolase activities, pre-B cell growth |- | CD158a | p58.1 | 50-58kD | IgSF, KIR family | NK subset, T subset | inhibition of NK cell cytolytic activity, MHC class-I specific NK receptor |- | CD158b | p58.2 | 50-58kD | IgSF, KIR family | NK subset, T subset | inhibition of NK cell cytolytic activity, MHC class-I specific NK receptor |- | CD159a | NKG2A | 43kD | T subset, NK | with CD94, NK cell receptor |- | CD159c | NKG2C | 40kD | Type II C-Type Lectin | NK | with MHC class I HLA-E molecules, forms heterodimer with CD94 |- | <a title="CD160 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD160 https://www.thermofisher.com/antibody/primary/target/CD160]">CD160</a> | BY55 | 27kD | IgSF | NK subset, T subset | costimulation |- | <a title="CD161 Products" href="[https://www.thermofisher.com/antibody/primary/target/NK1.1 https://www.thermofisher.com/antibody/primary/target/NK1.1]">CD161</a> | NKR-P1A | 40kD | C-type lectin | T subset, NK | NK cell-mediated cytotoxicity |- | <a title="CD162 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD162 https://www.thermofisher.com/antibody/primary/target/CD162]">CD162</a> | PSGL-1 | 120kD | Mucin family | mono, gran, most lymph | CD62P, CD62L ligand, adhesion, rolling |- | CD162R | PEN-5 | CHO | NK subset |- | <a title="CD163 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD163 https://www.thermofisher.com/antibody/primary/target/CD163]">CD163</a> | 130kD | Scavenger receptor SF | mono, mac |- | CD164 | MGC-24 | 80kD | epith, mono, lymph<sup>low</sup>, bone marrow stromal cells, CD34+ erythroid progenitors | hematopoietic progenitor cell-stromal cell interaction |- | CD165 | AD2, gp37 | 42kD | lymph subset, mono, immature thymocytes, platelets | adhesion, thymocyte-thymic epith interaction |- | <a title="CD166 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD166 https://www.thermofisher.com/antibody/primary/target/CD166]">CD166</a> | ALCAM | 105kD | IgSF | neurons, mono, epith, fibroblasts, Tact | CD6 ligand, adhesion |- | CD167a | DDR1 | 120kD | RTK family | epith, myoblasts | tyrosine kinase, adhesion to collagen |- | CD168 | RHAMM | 84-88kD | mono, T subset, thymocyte subset, intracellularly in breast cancer cells | adhesion, tumor migration, metastasis |- | <a title="CD169 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD169 https://www.thermofisher.com/antibody/primary/target/CD169]">CD169</a> | sialoadhesin, Siglec-1 | 185kD | IgSF, sialoadhesins | tissue mac subset | adhesion, cell-cell and cell-matrix interactions, binds CD227 on breast cancer cells and CD43 on T cells |- | CD170 | Siglec-5, CD33-like2 | 140kD | IgSF, sialoadhesins | Mac subset, neutrophils | adhesion |- | <a title="CD171 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD171 https://www.thermofisher.com/antibody/primary/target/CD171]">CD171</a> | L1 | 200-210kD | IgSF | CNS, PNS, glial cells, mono, T subset, B, DC, several human tumor cells | kidney morphogenesis, lymph node architecture, T costimulation, neurohistogenesis, homotypic interaction, binds CD9, CD24, CD56, CD142, CD166, integrins |- | <a title="CD172a Products" href="[https://www.thermofisher.com/antibody/primary/target/SIRP%20alpha https://www.thermofisher.com/antibody/primary/target/SIRP%20alpha]">CD172a</a> | SIRPgamma | 110kD | mono, T subset, stem cells | adhesion, complex with CD47 |- | CD172b | SIRPbeta, SIRB1 | 50kD | IgSF | mono and DC | negative regulation of RTK-coupled signaling |- | CD172g | SIRPgamma, SIRPB2 | 45-50kD | IgSF, ASV | mRNA: liver and at lower levels in many tissues | binds CD47 |- | CD173 | Blood group H type 2 | CHO | erythrocytes, stem cell subset, platelets |- | CD174 | Lewis Y | CHO | stem cells subset, epith |- | CD175 | Tn | CHO | stem cells subset |- | CD175s | Sialyl-Tn | CHO | erythroblasts |- | CD176 | Thomson Friedrenreich Ag | CHO | stem cell subset |- | <a title="CD177 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD177 https://www.thermofisher.com/antibody/primary/target/CD177]">CD177</a> | NB1 | 56-62kD | neutrophil subset |- | <a title="CD178 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD178 https://www.thermofisher.com/antibody/primary/target/CD178]">CD178</a> | FasL, CD95L | 38-42kD | TNFSF | Tact, testis | CD95 ligand, apoptosis, immune privilege, soluble form in serum |- | CD179a | V pre B | 16-18kD | IgSF | Pro- and Pre-B | B cell differentiation / signaling, with IgM |- | CD179b | Lambda 5 | 22kD | IgSF | Pro- and Pre-B | B cell differentiation / signaling, with IgM |- | <a title="CD180 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD180 https://www.thermofisher.com/antibody/primary/target/CD180]">CD180</a> | RP-105 | 95-105kD | LRRF, TLR family | B subset, mono, DC | B cell activation, LPS signaling, with MD-1 |- | <a title="CD181 Products" href="[https://www.thermofisher.com/antibody/primary/target/CXCR1 https://www.thermofisher.com/antibody/primary/target/CXCR1]">CD181</a> | CXCR1, IL-8RA | 39kD | GPCR1 family | neutrophils, basophils, NK, T subset, mono | binding of IL-8 induces chemotaxis of neutrophils |- | <a title="CD182 Products" href="[https://www.thermofisher.com/antibody/primary/target/CXCR2 https://www.thermofisher.com/antibody/primary/target/CXCR2]">CD182</a> | CXCR2, IL-8RB | 40kD | GPCR1 family | neutrophils, basophils, NK, T subset, mono | binding of IL-8 induces chemotaxis of neutrophils |- | <a title="CD183 Products" href="[https://www.thermofisher.com/antibody/primary/target/CXCR3 https://www.thermofisher.com/antibody/primary/target/CXCR3]">CD183</a> | CXCR3 | 40kD | TM7SF | eosinophils, Tact and NK, GM-CSF activated CD34+ progenitors | IP-10 , Mig and I-TAC receptor, T cell recruitment to inflammatory sites, enhancement of Th1 response |- | <a title="CD184 Products" href="[https://www.thermofisher.com/antibody/primary/target/CXCR4 https://www.thermofisher.com/antibody/primary/target/CXCR4]">CD184</a> | CXCR4, fusin | 45kD | TM7SF | B, DC, T subset, mono, endoth | SDF-1 receptor, X4 HIV-1 coreceptor |- | CD185 | CXCR5, BLR1 | 45kD | GPCR1 family | mature B and Burkitt Lymphoma cells | with chemokine BLC, possible regulatory function in Burkitt Lymphomagenesis and/or B differentiation, activation of mature B |- | CD186 | CXCR6, BONZO | 40kD | GPCR1 family | Tact | receptor for CXCL16 and coreceptor for SIV, strains of HIV-2 and m-tropic HIV-1 |- | CD191 | CCR1, MIP-1alphaR, RANTES-R | 39kD | GPCR1 family | T, mono, stem cell subset | binds C-C type chemokines and transduces signal by increasing intracellular calcium ion levels |- | CD192 | CCR2, MCP-1-R | 40kD | GPCR1 family | activated NK and mononuclear phagocytes, T subset, B, endoth | binds MCP-1, MCP-3 & MCP-4, alternative coreceptor with CD4 for HIV-1 infection |- | <a title="CD193 Products" href="[https://www.thermofisher.com/antibody/primary/target/CCR3 https://www.thermofisher.com/antibody/primary/target/CCR3]">CD193</a> | CCR3, CKR3 | 45kD | GPCR1 family | eosinophils, lower expression in neutrophils and mono, T subset | binds eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES & MIP-1delta, alternative coreceptor with CD4 for HIV-1 infection |- | <a title="CD195 Products" href="[https://www.thermofisher.com/antibody/primary/target/CCR5 https://www.thermofisher.com/antibody/primary/target/CCR5]">CD195</a> | CCR5 | 45kD | mono, T subset | MIP-1alpha, MIP-1beta and RANTES receptor, R5 HIV-1 coreceptor |- | <a title="CD196 Products" href="[https://www.thermofisher.com/antibody/primary/target/CCR6 https://www.thermofisher.com/antibody/primary/target/CCR6]">CD196</a> | CCR6, LARC receptor, DRY6 | 45kD | GPCR1 family | T subset, B, DC subset | binds MIP-3alpha/LARC |- | <a title="CD197 Products" href="[https://www.thermofisher.com/antibody/primary/target/CCR7 https://www.thermofisher.com/antibody/primary/target/CCR7]">CD197</a> | CCR7 | 45kD | T subset, DC Subset | 6Ckine and MIP-2beta receptor |- | CD198 | CCR8, GPRCY6, TER1 | 50kD | GPCR1 family | T, high expression in Th2, NK, mono | allergic inflammation, alternative coreceptor with CD4 for HIV-1 infection |- | <a title="CD199 Products" href="[https://www.thermofisher.com/antibody/primary/target/CCR9 https://www.thermofisher.com/antibody/primary/target/CCR9]">CD199</a> | CCR9, GPR-9-6 | 43kD | GPCR1 family | subset of memory T, lamina propria mononuclear cells | binds SCYA25/TECK, alternative coreceptor with CD4 for HIV-1 infection |- | <a title="CD200 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD200 https://www.thermofisher.com/antibody/primary/target/CD200]">CD200</a> | OX-2 | 45-50kD | thymocytes, endoth, B, Tact | inhibition of immune response |- | <a title="CD201 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD178 https://www.thermofisher.com/antibody/primary/target/CD178]">CD201</a> | EPC-R | 50kD | endoth subset | activated protein C receptor |- | <a title="CD202b Products" href="[https://www.thermofisher.com/antibody/primary/target/TEK https://www.thermofisher.com/antibody/primary/target/TEK]">CD202b</a> | Tie2, Tek | 150kD | RTK family | stem cells, endoth | angiopoietin-1 receptor |- | CD203c | NPP3 / PDNP3, ENpp1, PD-1b | 130-150kD | type II TM | basophils, mast cells, glioma cells, megakaryocytes | ectoenzyme, binding to and clearance of extracellular nucleotides |- | CD204 | Macrophage scavenger-R | 220kD | mac | endocytosis of macromolecules |- | <a title="CD205 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD205 https://www.thermofisher.com/antibody/primary/target/CD205]">CD205</a> | DEC-205 | 205kD | DC, thymic epith | DC, thymic epith |- | <a title="CD206 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD206 https://www.thermofisher.com/antibody/primary/target/CD206]">CD206</a> | macrophage mannose-R | 180kD | DC subset, mac, mono | phagocytosis and pinocytosis of mannose containing molecules |- | <a title="CD207 Products" href="[https://www.thermofisher.com/antibody/primary/target/Langerin https://www.thermofisher.com/antibody/primary/target/Langerin]">CD207</a> | Langerin | 40kD | Langerhans cells | endocytic receptor |- | CD208 | DC-LAMP | 70-90kD | DCact, interdigitating DC |- | <a title="CD209 Products" href="[https://www.thermofisher.com/antibody/primary/target/DC-SIGN https://www.thermofisher.com/antibody/primary/target/DC-SIGN]">CD209</a> | DC-SIGN | 44kD | DC subset | ICAM-3 receptor, HIV-1 binding protein |- | CD210 | IL-10-R | 90-110kD | T, B, NK, mono, mac | IL-10 receptor, signal transduction |- | CD212 | IL-12-R beta1 | 100kD | Tact and NK | binds IL-12 with high affinity, associates with IL-12 receptor beta2 |- | <a title="CD213a1 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL13RA1 https://www.thermofisher.com/antibody/primary/target/IL13RA1]">CD213a1</a> | IL-13-R alpha1 | 65kD | B, mono, fibroblasts, endoth | binds IL-13 with low affinity, with CD124 |- | CD213a2 | IL-13-R alpha2 | 65kD | B, mono | binds IL-13 with high affinity |- | <a title="CD217 Products" href="[https://www.thermofisher.com/antibody/primary/target/IL17RA https://www.thermofisher.com/antibody/primary/target/IL17RA]">CD217</a> | IL-17-R | 120kD | broad | IL-17 receptor |- | <a title="CD218a Products" href="[https://www.thermofisher.com/antibody/primary/target/IL18R1 https://www.thermofisher.com/antibody/primary/target/IL18R1]">CD218a</a> | IL-18Ralpha, IL-1Rrp | 70kD | IL-1R family | T, NK, DCs | binds IL-18, activation of NF-kappaB |- | CD218b | IL-18Rbeta, IL18RAP | 70kD | IL-1R family | T, NK and DCs | heterodimeric receptor with IL-18Ralpha to enhance IL-18 binding |- | CD220 | Insulin-R | 140, 70kD | broad | insulin receptor |- | <a title="CD221 Products" href="[https://www.thermofisher.com/antibody/primary/target/IGF1R%20alpha https://www.thermofisher.com/antibody/primary/target/IGF1R%20alpha]">CD221</a> | IGF-1 R | 140, 70kD | broad | binds IGF with high affinity, signaling, cell proliferation/ differentiation |- | CD222 | IGF-II R, mannose-6 phosphate-R | 250kD | Type I TM | broad, 90-95% intracellular | adhesion, tumor growth, a receptor for TGFbeta-LAP, plasminogen, proliferin, truncated form (220kD) found in serum |- | <a title="CD223 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD223 https://www.thermofisher.com/antibody/primary/target/CD223]">CD223</a> | LAG-3 | 70kD | IgSF | Tact and NK | an MHC class II ligand |- | CD224 | GGT | 27, 68kD | leukocytes, stem cells |- | CD225 | Leu-13 | 17kD | broad |- | <a title="CD226 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD226 https://www.thermofisher.com/antibody/primary/target/CD226]">CD226</a> | DNAM-1, PTA-1, TLiSA1 | 65kD | IgSF | T, NK, mono, platelets, activated HUVEC | activation of cell-mediated cytotoxicity, soluble form (50kD) found in normal serum |- | <a title="CD227 Products" href="[https://www.thermofisher.com/antibody/primary/target/MUC1 https://www.thermofisher.com/antibody/primary/target/MUC1]">CD227</a> | MUC1, EMA | 300kD | Mucin family, type I TM | epith, stem cell subset, FDC, mono, B subset, some myelomas | adhesion, signaling, binds CD169, CD54, & selectins |- | CD228 | Melanotransferrin | 80-95kD | stem cells, melanomas |- | <a title="CD229 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD229 https://www.thermofisher.com/antibody/primary/target/CD229]">CD229</a> | Ly-9 | 95, 110kD | IgSF | T, B | adhesion |- | <a title="CD230 Products" href="[https://www.thermofisher.com/antibody/primary/target/PrP https://www.thermofisher.com/antibody/primary/target/PrP]">CD230</a> | Prion protein | 35kD | broad |- | CD231 | TALLA-1, A15 | 30-45kD | TM4SF | T leukemias, neuroblastomas, brain neurons | marker for T cell acute lymphoblastic leukemia |- | CD232 | VESP-R | 200kD | broad |- | CD233 | Band 3, SLC4A1 | 90kD | Anion exchanger family | erythrocytes | anion exchanger pump, transport of CO2, linking red cell membrane to cytoskeleton |- | CD234 | Duffy, DARC | 35-45kD | erythrocytes | Duffy antigen chemokine receptor |- | <a title="CD235a Products" href="[https://www.thermofisher.com/antibody/primary/target/CD235a https://www.thermofisher.com/antibody/primary/target/CD235a]">CD235a</a> | Glycophorin A | 36kD | erythrocytes |- | CD235ab | Glycophorin A/B | 20kD | erythrocytes |- | CD235b | Glycophorin B | 20kD | erythrocytes |- | CD236 | Glycophorin C/D | 32, 23kD | erythrocytes, stem cell subset |- | CD236R | Glycophorin C | 32kD | erythrocytes, stem cell subset |- | CD238 | Kell | 93kD | erythrocytes, stem cell subset |- | CD239 | B-CAM | 78-85kD | erythrocytes, stem cell subset |- | CD240CE | Rh30CE | 30-32kD | erythrocytes |- | CD240D | Rh30D | 30-32kD | TM12SF | erythrocytes |- | CD241 | RhAg, Rh50 | 50kD | TM12SF | erythrocytes | complex with CD47, LW, glycophorin B |- | CD242 | ICAM-4 | 42kD | IgSF | erythrocytes | adhesion, Landsteiner-Wiener blood group |- | <a title="CD243 Products" href="[https://www.thermofisher.com/antibody/primary/target/P-Glycoprotein https://www.thermofisher.com/antibody/primary/target/P-Glycoprotein]">CD243</a> | MDR-1, p170, P-gp | 180kD | stem cells, small intestine, kidney stem cells, small intestine, kidney | ion pump |- | <a title="CD244 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD244 https://www.thermofisher.com/antibody/primary/target/CD244]">CD244</a> | 2B4 | 70kD | type II TM | T subset, mono, basophils, NK | NK activation, CD48 ligand |- | CD245 | p220/240 | 220-240kD | T subset |- | CD246 | ALK, Ki-1 | 80kD | anaplastic T cell leukemias, small intestine, testis, brain, not on normal lymph | brain development, implicated in ALK lymphomas |- | <a title="CD247 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD3z https://www.thermofisher.com/antibody/primary/target/CD3z]">CD247</a> | TCRz | 16kD | RTK family | T, NK | TCR complex subunit, coupling of antigen recognition to signaling |- | CD248 | TEM1, Endosialin | 175kD | C-Type Lectin | endothelial tissue, stromal fibroblasts | tumor progression and angiogenesis |- | CD249 | Aminopeptidase A | 160kD | Peptidase M1 family | epith, endoth | renin-angiotensin system |- | <a title="CD252 Products" href="[https://www.thermofisher.com/antibody/primary/target/OX40L https://www.thermofisher.com/antibody/primary/target/OX40L]">CD252</a> | OX-40Ligand, gp34 | 34kD | TNFSF | B<sup>act</sup>, cardiac myocytes | T costimulation |- | <a title="CD253 Products" href="[https://www.thermofisher.com/antibody/primary/target/TRAIL https://www.thermofisher.com/antibody/primary/target/TRAIL]">CD253</a> | TRAIL, Apo-2L, TL2, TNFSF10 | TNFSF | Tact, many tissues | death |- | <a title="CD254 Products" href="[https://www.thermofisher.com/antibody/primary/target/RANKL https://www.thermofisher.com/antibody/primary/target/RANKL]">CD254</a> | TRANCE, RANKL, OPGL | 35kD | TNFSF | lymph node & BM stroma Tact | binds OPG and RANK, osteoclast differentiation, enhances DC to stimulate naïve-T proliferation |- | CD256 | APRIL, TALL-2 | 16kD | TNFSF | mono, mac | binds TACI & BCMA, B proliferation |- | <a title="CD257 Products" href="[https://www.thermofisher.com/antibody/primary/target/BAFF https://www.thermofisher.com/antibody/primary/target/BAFF]">CD257</a> | BLyS, BAFF, TALL-1 | TNFSF | mono<sup>act</sup>, soluble form | B cell growth factor & costimulator of Ig production |- | <a title="CD258 Products" href="[https://www.thermofisher.com/antibody/primary/target/LIGHT https://www.thermofisher.com/antibody/primary/target/LIGHT]">CD258</a> | LIGHT, HVEM-L | 28kD | TNFSF | Tact, immature DC | binds LTBR, T proliferation, receptor for HVEM |- | <a title="CD261 Products" href="[https://www.thermofisher.com/antibody/primary/target/DR4 https://www.thermofisher.com/antibody/primary/target/DR4]">CD261</a> | TRAIL-R1, DR4 | 57kD | TNFRSF | Tact, peripheral blood leukocytes | contains death domain, apoptosis via FADD & caspase-8 |- | <a title="CD262 Products" href="[https://www.thermofisher.com/antibody/primary/target/DR5 https://www.thermofisher.com/antibody/primary/target/DR5]">CD262</a> | TRAIL-R2, DR5 | 60kD | TNFRSF | widely expressed, peripheral blood lymphocytes | contains death domain, apoptosis via FADD and caspase-8 |- | <a title="CD263 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD263 https://www.thermofisher.com/antibody/primary/target/CD263]">CD263</a> | TRAIL-R3, DcR1, LIT | 65kD | TNFRSF | peripheral blood lymphocytes | receptor for TRAIL but lacks death domain |- | <a title="CD265 Products" href="[https://www.thermofisher.com/antibody/primary/target/RANK https://www.thermofisher.com/antibody/primary/target/RANK]">CD265</a> | RANK, TRANCE-R, ODFR | 97kD | TNFRSF | broad expression | binds TRANCE, osteoclastogenesis, T-DC interactions |- | <a title="CD266 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD266 https://www.thermofisher.com/antibody/primary/target/CD266]">CD266</a> | TWEAK-R, FGF-inducible 14 | 14kD | TNFRSF | heart, placenta and kidney, HUVEC | TWEAK receptor, cell-matrix interactions and endoth growth and migration |- | <a title="CD267 Products" href="[https://www.thermofisher.com/antibody/primary/target/TNFRSF13B https://www.thermofisher.com/antibody/primary/target/TNFRSF13B]">CD267</a> | TACI, TNFR SF13B | B, Tact | binds BAFF & APRIL |- | <a title="CD268 Products" href="[https://www.thermofisher.com/antibody/primary/target/TNFRSF13B https://www.thermofisher.com/antibody/primary/target/TNFRSF13B]">CD268</a> | BAFFR, TR13C | 25kD | TNFRSF | B | binds BLyS, mature B survival |- | CD269 | BCMA, TNFRSF13B | 20kD | TNFRSF | mature B (membrane and perinuclear) | APRIL & BAFF receptor, B survival & proliferation |- | CD271 | NGFR, p75 (NTR) | 45kD | TNFRSF | neurons (schwann cells, growing neurites), BM mesenchymal cells | NGF, BDNF, NT-3, & NT-4 receptor, tumor suppressor, cell survival and death |- | <a title="CD272 Products" href="[https://www.thermofisher.com/antibody/primary/target/BTLA https://www.thermofisher.com/antibody/primary/target/BTLA]">CD272</a> | BTLA | 33kD | IgSF | Tact, B , remains on Th1 | HVEM receptor, inhibitory response |- | <a title="CD273 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD273 https://www.thermofisher.com/antibody/primary/target/CD273]">CD273</a> | B7DC, PD-L2, PDCD1L2 | 25kD | IgSF | DC subset, mono, mac | PD-1 receptor, costimulation or suppression of T proliferation |- | <a title="CD274 Products" href="[https://www.thermofisher.com/antibody/primary/target/PD-L1 https://www.thermofisher.com/antibody/primary/target/PD-L1]">CD274</a> | B7-H1, PD-L1 | 33kD | IgSF | leukocytes, broad | PD-1 receptor, costimulation of lymphocytes |- | <a title="CD275 Products" href="[https://www.thermofisher.com/antibody/primary/target/ICOSLG https://www.thermofisher.com/antibody/primary/target/ICOSLG]">CD275</a> | B7-H2, ICOSL, B7-RP1, GL50 | 60kD | B7 Family | B, DC, mono | costimulation, cytokine production |- | <a title="CD276 Products" href="[https://www.thermofisher.com/antibody/primary/target/B7-H3 https://www.thermofisher.com/antibody/primary/target/B7-H3]">CD276</a> | B7-H3 | 40-45kD | B7 Family, ASV | in vitro cultured DC and mono, Tact, mammary tissue | costimulation, T activation |- | <a title="CD277 Products" href="[https://www.thermofisher.com/antibody/primary/target/BTN3A1 https://www.thermofisher.com/antibody/primary/target/BTN3A1]">CD277</a> | BT3.1, butyrophilin SF3 A1, BTF5 | 56kD | B7/BT family, ASV | T, B, NK, mono, DC, endoth, CD34+ cells, tumor cell lines | T activation |- | <a title="CD278 Products" href="[https://www.thermofisher.com/antibody/primary/target/ICOS https://www.thermofisher.com/antibody/primary/target/ICOS]">CD278</a> | ICOS, AILIM | 55-60kD | CD28 family | Tact, Th2 | binds ICOS-L, T costimulation |- | <a title="CD279 Products" href="[https://www.thermofisher.com/antibody/primary/target/PD-1 https://www.thermofisher.com/antibody/primary/target/PD-1]">CD279</a> | PD1, SLEB2 | 55kD | Tact and B<sup>act</sup> | B7-H1 & B7-DC receptor, autoimmune disease and peripheral tolerance |- | CD280 | ENDO180, UPARAP | 180kD | C-type lectin SF | chondrocytes, fibroblasts, endothelial, mac | mannose receptor, collagen matrix remodeling and endocytic recycling |- | <a title="CD281 Products" href="[https://www.thermofisher.com/antibody/primary/target/TLR1 https://www.thermofisher.com/antibody/primary/target/TLR1]">CD281</a> | TLR1 | 90kD | TLR family | low levels in PBMC, mono and possibly DC | innate immunity, with TLR2 |- | <a title="CD282 Products" href="[https://www.thermofisher.com/antibody/primary/target/TLR2 https://www.thermofisher.com/antibody/primary/target/TLR2]">CD282</a> | TLR2 | 90kD | TLR family | mono, neutrophil, upregulated in mac | binds dsRNA, response to bacterial lipoproteins, innate immunity |- | <a title="CD283 Products" href="[https://www.thermofisher.com/antibody/primary/target/TLR3 https://www.thermofisher.com/antibody/primary/target/TLR3]">CD283</a> | TLR3 | 100kD | TLR family, ASV | derived moDC (may be intracellular) | binds dsRNA, innate immunity |- | <a title="CD284 Products" href="[https://www.thermofisher.com/antibody/primary/target/TLR4 https://www.thermofisher.com/antibody/primary/target/TLR4]">CD284</a> | TLR4 | 100kD | TLR family, ASV | PBMC (weak in mono, immature DC & neutro) | binds LPS, innate immunity |- | <a title="CD289 Products" href="[https://www.thermofisher.com/antibody/primary/target/TLR9 https://www.thermofisher.com/antibody/primary/target/TLR9]">CD289</a> | TLR9 | 120kD | TLR family | pDC (intracellular) | binds CpG-DNA, innate immunity |- | CD292 | BMPR1A, ALK3 | 57kD | Type I | bone progenitor | BMP 2 & 4 receptor, bone development |- | CD293 | BMPR1B, ALK6 | 57kD | Type I, ASV | bone progenitor | BMP receptor, bone development |- | <a title="CD Products" href="[https://www.thermofisher.com/antibody/primary/target/CRTH2 https://www.thermofisher.com/antibody/primary/target/CRTH2]">CD294</a> | CRTH2. GPR44 | 55-70kD | GPCR-7TM | Th2, eosinophils, basophils | binds prostaglandin D2, stimulatory effects on Th2, allergic inflammation |- | CD295 | LeptinR, LEPR | 132kD | Type I cytokine-like receptor | broad | adipose metabolism, immune dysfunction in obesity |- | CD296 | ART1, RT6, ART2 | 37kD | ADP- ribosyltransferase | heart and skeletal muscle, peripheral T, NK subset | modifies integrins during differentiation, ADP ribosylation of target proteins |- | CD297 | ART4, dombrock blood group | 38kD | ADP- ribosyltransferase | erythroid, mono<sup>act</sup> | ADP ribosylation of target proteins |- | CD298 | Na+/K+-ATPase beta3 subunit | 52kD | broad | transport sodium & potassium ions across membrane |- | CD299 | DC-SIGN-related, LSIGN, DC-SIGN2 | 45kD | Type II, similar to CD209, ASV | endothelial subset | binds ICAM3, HIV-1 gp120, coreceptor with DC-SIGN, HIV infection |- | CD300a | CMRF35H, IRC1, IRp60 | 60kD | IgSF, ASV | NK, mono, neutrophils, T and B subset and lymphocytic cell lines, AML | unknown |- | <a title="CD300c Products" href="[https://www.thermofisher.com/antibody/primary/target/CD300c https://www.thermofisher.com/antibody/primary/target/CD300c]">CD300c</a> | CMRF35A, LIR | IgSF | mono, neutrophils, monocytic cell lines, B & T subsets | unknown |- | <a title="CD300e Products" href="[https://www.thermofisher.com/antibody/primary/target/CD300e https://www.thermofisher.com/antibody/primary/target/CD300e]">CD300e</a> | CMRF35L | IgSF CMRF family | unknown |- | CD301 | MGL, HML | 38kD | C type lectin SF, ASV | immature DC | binds Tn antigen, uptake of glycosylated antigens |- | CD302 | DCL1, BIMLEC | 19-28kD | Type I TM C-type lectin receptor | some myeloid and Hodgkin’s cell lines | a fusion protein in Hodgkin’s lymphoma with DEC-205 |- | CD303 | BDCA2, HECL | 38kD | C-type lectin SF ASV | plasmacytoid dendritic cells | inhibit IFN-alpha production |- | CD304 | BDCA4, neuropilin 1 | 130kD | semaphorin family | neurons, CD4+/CD25+ Treg, DC, endothelial and tumor cells | interacts with VEGF165 & semaphorins, co-receptor with plexin, axonal guidance, angiogenesis, cell survival, migration |- | <a title="CD305 Products" href="[https://www.thermofisher.com/antibody/primary/target/LAIR1 https://www.thermofisher.com/antibody/primary/target/LAIR1]">CD305</a> | LAIR1 | 32-40kD | IgSF, ASV | NK, B, T, mono | inhibitory receptor on NK and T cells |- | CD306 | LAIR2 | IgSF, ASV | unknown | soluble, mucosal tolerance |- | CD307 | IRTA2 | 55-105kD | IgSF (Fc receptor), ASV | B subset, B lymphoma | B cell development, translocation in some lymphomas |- | <a title="CD309 Products" href="[https://www.thermofisher.com/antibody/primary/target/VEGF%20Receptor%202 https://www.thermofisher.com/antibody/primary/target/VEGF%20Receptor%202]">CD309</a> | VEGFR2, KDR | 230kD | Type III TM tyr kinase | endothelial, angiogenic precursor cells, hemangioblast | binds VEGF, regulates adhesion and cell signaling |- | CD312 | EMR2 | 90kD | EGFR-7TM ASV | mono, mac, moDC, grans<sup>low</sup> | cell adhesion and migration for phagocytosis |- | <a title="CD314 Products" href="[https://www.thermofisher.com/antibody/primary/target/NKG2D https://www.thermofisher.com/antibody/primary/target/NKG2D]">CD314</a> | NKG2D, KLR | 42kD | Type II lectin-like receptor | NK, CD8+ activated, NK1.1+ T, some myeloid cells | binds MHC class I, MICA, MICB, Rae1 & ULBP4, activates cytolysis and cytokine production, costimulation |- | CD315 | CD9P1, SMAP6, FPRP, PTGFRN | 135kD | IgSF | B subset, mono<sup>act</sup> | with CD81 and CD9 |- | CD316 | EWI2, PGRL, CD81P3, KASP | 63-75kD | IgSF8 | B, T cells, low on NK cells | with CD81 & CD9; involved in cell migration |- | <a title="CD317 Products" href="[https://www.thermofisher.com/antibody/primary/target/BST-2 https://www.thermofisher.com/antibody/primary/target/BST-2]">CD317</a> | BST2, HM1.24 | 30-36kD | Type II | B, T, NK, mono, DC, fibroblast cell line, myeloma | pre-B cell growth, overexpressed in multiple myeloma |- | CD318 | CDCP1, SIMA135 | 135kD | Type I, ASV | HSC (subset of CD34+), tumors | cell adhesion with ECM |- | <a title="CD319 Products" href="[https://www.thermofisher.com/antibody/primary/target/CRACC https://www.thermofisher.com/antibody/primary/target/CRACC]">CD319</a> | CRACC, SLAMF7 | 66kD | Ig TM | T, B and DC subset, NK, upregulated in DC | regulate T and NK cells |- | CD320 | 8D6A, 8D6 | 30kD | LDL receptor | follicular DC, germinal centers | B proliferation, tumor formation |- | <a title="CD321 Products" href="[https://www.thermofisher.com/antibody/primary/target/JAM1 https://www.thermofisher.com/antibody/primary/target/JAM1]">CD321</a> | JAM1, F11 receptor | 35kD | IgSF, Type I, ASV | platelet receptor, epithelia and endothelial, platelets | tight junctions |- | CD322 | JAM2, VE-JAM | 43kD | IgSF | HEV, other endoth | cell adhesion, lymphocyte homing to secondary lymphoid organs |- | <a title="CD324 Products" href="[https://www.thermofisher.com/antibody/primary/target/E-cadherin https://www.thermofisher.com/antibody/primary/target/E-cadherin]">CD324</a> | E-Cadherin, Uvomorulin | 120kD | cadherin SF | non-neural epith | cell adhesion, homotypic interaction & binds alphaE/beta7 |- | <a title="CD325 Products" href="[https://www.thermofisher.com/antibody/primary/target/N-cadherin https://www.thermofisher.com/antibody/primary/target/N-cadherin]">CD325</a> | N-Cadherin, NCAD | 140kD | cadherin SF | brain, skeletal and cardiac muscle | cell adhesion, neuronal recognition |- | <a title="CD326 Products" href="[https://www.thermofisher.com/antibody/primary/target/EpCAM https://www.thermofisher.com/antibody/primary/target/EpCAM]">CD326</a> | Ep-CAM, Ly74 | 35-40kD | most epith cell membranes | growth factor receptor? |- | CD327 | SIGLEC6 | IgSF | placenta, spleen, B . sialic-acid dependent | adhesion, membrane- bound & secreted forms |- | <a title="CD328 Products" href="[https://www.thermofisher.com/antibody/primary/target/SIGLEC7 https://www.thermofisher.com/antibody/primary/target/SIGLEC7]">CD328</a> | SIGLEC7, AIRM-1 | 75kD | IgSF | resting and activated NK, placenta, liver, spleen, lower in gran & mono | sialic-acid dependent adhesion, inhibit NK activation, hemopoiesis |- | CD329 | SIGLEC9 | IgSF | neutrophils and mono | sialic-acid dependent adhesion molecule |- | CD331 | FGFR1, Fms-like tyrosine kinase-2, KAL2, N-SAM | 30kD | TM tyr kinase | fibroblasts, epithelial | binds FGF, high affinity receptor for fibroblast growth factors |- | CD332 | FGFR2, BEK, KGFR | 115-135kD | TM RTK family | fibroblasts, epithelial | binds FGF, high affinity receptor for fibroblast growth factors |- | CD333 | FGFR3, ACH, CEK2 | 115kD | TM RTK family | fibroblasts, epithelial | binds FGF, high affinity receptor for fibroblast growth factors |- | CD334 | FGFR4, JTK2, TKF | 110kD | TM RTK family | fibroblasts, epithelial | binds FGF, high affinity receptor for fibroblast growth factors |- | <a title="CD335 Products" href="[https://www.thermofisher.com/antibody/primary/target/NKp46 https://www.thermofisher.com/antibody/primary/target/NKp46]">CD335</a> | NKp46, Ly-94 homolog | 46kD | IgSF | NK | activates NK cells upon non-MHC ligand binding |- | CD336 | NKp44, Ly-95 homolog | 44kD | IgSF | NK | activates NK cells upon non-MHC ligand binding |- | CD337 | NKp30, Ly117 | 30kD | IgSF | NK | activates NK cells upon non-MHC ligand binding |- | <a title="CD338 Products" href="[https://www.thermofisher.com/antibody/primary/target/CD338 https://www.thermofisher.com/antibody/primary/target/CD338]">CD338</a> | ABCG2, BCRP, Bcrp1, MXR | 73kD | GPCR 7TM | stem cell subset (side population) | multi-drug resistance transporter |- | <a title="CD339 Products" href="[https://www.thermofisher.com/antibody/primary/target/Jagged1 https://www.thermofisher.com/antibody/primary/target/Jagged1]">CD339</a> | Jagged-1, JAG1, JAGL1, hJ1 | 135kD | EGF TM | stromal cells, epithelial, AML | binds Notch, hematopoiesis |} </div></div>[[Category:Antibodies]]
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