CD19

NM_001770
B-lymphocyte antigen CD19 isoform 2 precursor
ATGCCACCTCCTCGCCTCCTCTTCTTCCTCCTCTTCCTCACCCCCATGGAAGTCAGGCCCGAGGAACCTCTAGTGGTGAAGGTGGAAGAGGGAGATAACGCTGTGCTGCAGTGCCTCAAGGGGACCTCAGATGGCCCCACTCAGCAGCTGACCTGGTCTCGGGAGTCCCCGCTTAAACCCTTCTTAAAACTCAGCCTGGGGCTGCCAGGCCTGGGAATCCACATGAGGCCCCTGGCCATCTGGCTTTTCATCTTCAACGTCTCTCAACAGATGGGGGGCTTCTACCTGTGCCAGCCGGGGCCCCCCTCTGAGAAGGCCTGGCAGCCTGGCTGGACAGTCAATGTGGAGGGCAGCGGGGAGCTGTTCCGGTGGAATGTTTCGGACCTAGGTGGCCTGGGCTGTGGCCTGAAGAACAGGTCCTCAGAGGGCCCCAGCTCCCCTTCCGGGAAGCTCATGAGCCCCAAGCTGTATGTGTGGGCCAAAGACCGCCCTGAGATCTGGGAGGGAGAGCCTCCGTGTCTCCCACCGAGGGACAGCCTGAACCAGAGCCTCAGCCAGGACCTCACCATGGCCCCTGGCTCCACACTCTGGCTGTCCTGTGGGGTACCCCCTGACTCTGTGTCCAGGGGCCCCCTCTCCTGGACCCATGTGCACCCCAAGGGGCCTAAGTCATTGCTGAGCCTAGAGCTGAAGGACGATCGCCCGGCCAGAGATATGTGGGTAATGGAGACGGGTCTGTTGTTGCCCCGGGCCACAGCTCAAGACGCTGGAAAGTATTATTGTCACCGTGGCAACCTGACCATGTCATTCCACCTGGAGATCACTGCTCGGCCAGTACTATGGCACTGGCTGCTGAGGACTGGTGGCTGGAAGGTCTCAGCTGTGACTTTGGCTTATCTGATCTTCTGCCTGTGTTCCCTTGTGGGCATTCTTCATCTTCAAAGAGCCCTGGTCCTGAGGAGGAAAAGAAAGCGAATGACTGACCCCACCAGGAGATTCTTCAAAGTGACGCCTCCCCCAGGAAGCGGGCCCCAGAACCAGTACGGGAACGTGCTGTCTCTCCCCACACCCACCTCAGGCCTCGGACGCGCCCAGCGTTGGGCCGCAGGCCTGGGGGGCACTGCCCCGTCTTATGGAAACCCGAGCAGCGACGTCCAGGCGGATGGAGCCTTGGGGTCCCGGAGCCCGCCGGGAGTGGGCCCAGAAGAAGAGGAAGGGGAGGGCTATGAGGAACCTGACAGTGAGGAGGACTCCGAGTTCTATGAGAACGACTCCAACCTTGGGCAGGACCAGCTCTCCCAGGATGGCAGCGGCTACGAGAACCCTGAGGATGAGCCCCTGGGTCCTGAGGATGAAGACTCCTTCTCCAACGCTGAGTCTTATGAGAACGAGGATGAAGAGCTGACCCAGCCGGTCGCCAGGACAATGGACTTCCTGAGCCCTCATGGGTCAGCCTGGGACCCCAGCCGGGAAGCAACCTCCCTGGGGTCCCAGTCCTATGAGGATATGAGAGGAATCCTGTATGCAGCCCCCCAGCTCCGCTCCATTCGGGGCCAGCCTGGACCCAATCATGAGGAAGATGCAGACTCTTATGAGAACATGGATAATCCCGATGGGCCAGACCCAGCCTGGGGAGGAGGGGGCCGCATGGGCACCTGGAGCACCAGGTGA


atgccacctcctcgcctcctcttcttcctcctcttcctcacccccatggaagtcagg
  M  P  P  P  R  L  L  F  F  L  L  F  L  T  P  M  E  V  R  

cccgaggaacctctagtggtgaaggtggaagagggagataacgctgtgctgcagtgcctcaag
 P  E  E  P  L  V  V  K  V  E  E  G  D  N  A  V  L  Q  C  L  K 
gggacctcagatggccccactcagcagctgacctggtctcgggagtccccgcttaaaccc
 G  T  S  D  G  P  T  Q  Q  L  T  W  S  R  E  S  P  L  K  P 
ttcttaaaactcagcctggggctgccaggcctgggaatccacatgaggcccctggccatc
 F  L  K  L  S  L  G  L  P  G  L  G  I  H  M  R  P  L  A  I 
tggcttttcatcttcaacgtctctcaacagatggggggcttctacctgtgccagccgggg
 W  L  F  I  F  N  V  S  Q  Q  M  G  G  F  Y  L  C  Q  P  G 
cccccctctgagaaggcctggcagcctggctggacagtcaatgtggagggcagcggggag
 P  P  S  E  K  A  W  Q  P  G  W  T  V  N  V  E  G  S  G  E 
ctgttccggtggaatgtttcggacctaggtggcctgggctgtggcctgaagaacaggtcc
 L  F  R  W  N  V  S  D  L  G  G  L  G  C  G  L  K  N  R  S 
tcagagggccccagctccccttccgggaagctcatgagccccaagctgtatgtgtgggcc
 S  E  G  P  S  S  P  S  G  K  L  M  S  P  K  L  Y  V  W  A 
aaagaccgccctgagatctgggagggagagcctccgtgtctcccaccgagggacagcctg
 K  D  R  P  E  I  W  E  G  E  P  P  C  L  P  P  R  D  S  L 
aaccagagcctcagccaggacctcaccatggcccctggctccacactctggctgtcctgt
 N  Q  S  L  S  Q  D  L  T  M  A  P  G  S  T  L  W  L  S  C 
ggggtaccccctgactctgtgtccaggggccccctctcctggacccatgtgcaccccaag
 G  V  P  P  D  S  V  S  R  G  P  L  S  W  T  H  V  H  P  K 
gggcctaagtcattgctgagcctagagctgaaggacgatcgcccggccagagatatgtgg
 G  P  K  S  L  L  S  L  E  L  K  D  D  R  P  A  R  D  M  W 
gtaatggagacgggtctgttgttgccccgggccacagctcaagacgctggaaagtattat
 V  M  E  T  G  L  L  L  P  R  A  T  A  Q  D  A  G  K  Y  Y 
tgtcaccgtggcaacctgaccatgtcattccacctggagatcactgctcggccagtacta
 C  H  R  G  N  L  T  M  S  F  H  L  E  I  T  A  R  P  V  L 
tggcactggctgctgaggactggtggctggaag
 W  H  W  L  L  R  T  G  G  W  K 


gtctcagctgtgactttggcttatctgatcttctgcctgtgttcccttgtgggcattcttcatctt
 V  S  A  V  T  L  A  Y  L  I  F  C  L  C  S  L  V  G  I  L  H  L 


caaagagccctggtcctgagg
 Q  R  A  L  V  L  R 
aggaaaagaaagcgaatgactgaccccaccaggagattcttcaaagtgacgcctccccca
 R  K  R  K  R  M  T  D  P  T  R  R  F  F  K  V  T  P  P  P 
ggaagcgggccccagaaccagtacgggaacgtgctgtctctccccacacccacctcaggc
 G  S  G  P  Q  N  Q  Y  G  N  V  L  S  L  P  T  P  T  S  G 
ctcggacgcgcccagcgttgggccgcaggcctggggggcactgccccgtcttatggaaac
 L  G  R  A  Q  R  W  A  A  G  L  G  G  T  A  P  S  Y  G  N 
ccgagcagcgacgtccaggcggatggagccttggggtcccggagcccgccgggagtgggc
 P  S  S  D  V  Q  A  D  G  A  L  G  S  R  S  P  P  G  V  G 
ccagaagaagaggaaggggagggctatgaggaacctgacagtgaggaggactccgagttc
 P  E  E  E  E  G  E  G  Y  E  E  P  D  S  E  E  D  S  E  F 
tatgagaacgactccaaccttgggcaggaccagctctcccaggatggcagcggctacgag
 Y  E  N  D  S  N  L  G  Q  D  Q  L  S  Q  D  G  S  G  Y  E 
aaccctgaggatgagcccctgggtcctgaggatgaagactccttctccaacgctgagtct
 N  P  E  D  E  P  L  G  P  E  D  E  D  S  F  S  N  A  E  S 
tatgagaacgaggatgaagagctgacccagccggtcgccaggacaatggacttcctgagc
 Y  E  N  E  D  E  E  L  T  Q  P  V  A  R  T  M  D  F  L  S 
cctcatgggtcagcctgggaccccagccgggaagcaacctccctggggtcccagtcctat
 P  H  G  S  A  W  D  P  S  R  E  A  T  S  L  G  S  Q  S  Y 
gaggatatgagaggaatcctgtatgcagccccccagctccgctccattcggggccagcct
 E  D  M  R  G  I  L  Y  A  A  P  Q  L  R  S  I  R  G  Q  P 
ggacccaatcatgaggaagatgcagactcttatgagaacatggataatcccgatgggcca
 G  P  N  H  E  E  D  A  D  S  Y  E  N  M  D  N  P  D  G  P 
gacccagcctggggaggagggggccgcatgggcacctggagcaccaggtga
 D  P  A  W  G  G  G  G  R  M  G  T  W  S  T  R  - 

MPPPRLLFFLLFLTPMEVR

extracullular
PEEPLVVKVEEGDNAVLQCLKGTSD
GPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPP
SEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWA
KDRPEIWEGEPPCLPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVH
PKGPKSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITA
RPVLWHWLLRTGGWK

transmembrane
VSAVTLAYLIFCLCSLVGILHL

cytoplasmid
QRALVLRRKRKRMTDPTRRFF
KVTPPPGSGPQNQYGNVLSLPTPTSGLGRAQRWAAGLGGTAPSYGNPSSDVQADGALG
SRSPPGVGPEEEEGEGYEEPDSEEDSEFYENDSNLGQDQLSQDGSGYENPEDEPLGPE
DEDSFSNAESYENEDEELTQPVARTMDFLSPHGSAWDPSREATSLGSQSYEDMRGILY
AAPQLRSIRGQPGPNHEEDADSYENMDNPDGPDPAWGGGGRMGTWSTR

Topologica domain	20 – 291	Extracellular 	272
Transmembrane	292 – 313	Helical  		22
Topological domain	314 – 556	Cytoplasmic  243