PD-1

Topological  21 – 170	Extracellular 	150
Transmembrane 	171 – 191	Helical 		21
Topological  192 – 288	Cytoplasmic 97

MQIPQAPWPVVWAVLQLGWR

PGWFLDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLA
AFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRA
ELRVTERRAEVPTAHPSPSPRPAGQFQTLV

VGVVGGLLGSLVLLVWVLAVI

CSRAARGTIGARRTGQPLKEDPSAVPVFSVDYGELDFQWREKTPEPPVPCVPEQTEYATI
VFPSGMGTSSPARRGSADGPRSAQPLRPEDGHCSWPL


atgcagatcccacaggcgccctggccagtcgtctgggcggtgctacaactgggctggcgg
 M  Q  I  P  Q  A  P  W  P  V  V  W  A  V  L  Q  L  G  W  R 


ccaggatggttcttagactccccagacaggccctggaacccccccaccttctccccagcc
 P  G  W  F  L  D  S  P  D  R  P  W  N  P  P  T  F  S  P  A 
ctgctcgtggtgaccgaaggggacaacgccaccttcacctgcagcttctccaacacatcg
 L  L  V  V  T  E  G  D  N  A  T  F  T  C  S  F  S  N  T  S 
gagagcttcgtgctaaactggtaccgcatgagccccagcaaccagacggacaagctggcc
 E  S  F  V  L  N  W  Y  R  M  S  P  S  N  Q  T  D  K  L  A 
gccttccccgaggaccgcagccagcccggccaggactgccgcttccgtgtcacacaactg
 A  F  P  E  D  R  S  Q  P  G  Q  D  C  R  F  R  V  T  Q  L 
cccaacgggcgtgacttccacatgagcgtggtcagggcccggcgcaatgacagcggcacc
 P  N  G  R  D  F  H  M  S  V  V  R  A  R  R  N  D  S  G  T 
tacctctgtggggccatctccctggcccccaaggcgcagatcaaagagagcctgcgggca
 Y  L  C  G  A  I  S  L  A  P  K  A  Q  I  K  E  S  L  R  A 
gagctcagggtgacagagagaagggcagaagtgcccacagcccaccccagcccctcaccc
 E  L  R  V  T  E  R  R  A  E  V  P  T  A  H  P  S  P  S  P 
aggccagccggccagttccaaaccctggtg
 R  P  A  G  Q  F  Q  T  L  V  


gttggtgtcgtgggcggcctgctgggcagcctggtgctgctagtctgggtcctggccgtcatc
 V  G  V  V  G  G  L  L  G  S  L  V  L  L  V  W  V  L  A  V  I 



tgctcccgggccgcacgagggacaata
 C  S  R  A  A  R  G  T  I 
ggagccaggcgcaccggccagcccctgaaggaggacccctcagccgtgcctgtgttctct
 G  A  R  R  T  G  Q  P  L  K  E  D  P  S  A  V  P  V  F  S 
gtggactatggggagctggatttccagtggcgagagaagaccccggagccccccgtgccc
 V  D  Y  G  E  L  D  F  Q  W  R  E  K  T  P  E  P  P  V  P 
tgtgtccctgagcagacggagtatgccaccattgtctttcctagcggaatgggcacctca
 C  V  P  E  Q  T  E  Y  A  T  I  V  F  P  S  G  M  G  T  S 
tcccccgcccgcaggggctcagccgacggccctcggagtgcccagccactgaggcctgag
 S  P  A  R  R  G  S  A  D  G  P  R  S  A  Q  P  L  R  P  E 
gatggacactgctcttggcccctctga
 D  G  H  C  S  W  P  L  -