Rabbit monoclonal antibody

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The basic schedule would be as follows:

Day 0 Pre-bleed/Immunize

Day 21 Boost

Day 31 Production Bleed

Day 42 Boost

Day 52 Production Bleed

TBD Exsanguination/Tissue harvest

(optional )Add a harvest boost five days before spleen and bone marrow harvest.


If you decide to boost for a longer period at the end of the study,
we can determine a custom protocol for that extension.


For the protein, it would be best to have 100ug/animal/immunization for a total of 300ug/animal for the study.

If you have data to use less (I saw 30ug mentioned) then you could consider that also.
For the cells, I agree that 1 million cells/immunization would be an acceptable amount.


Antibodies