SpyCatcher Spytag

Summary of Catcher-Tag technologies and their development.

Catcher	Tag	Tag Sequence	Description	Publication Year
SpyCatcher	SpyTag	AHIVMVDAYKPTK	Original Catcher-Tag technology.	2012
SpyCatcher ΔN1ΔC1	SpyTag	AHIVMVDAYKPTK	Minimal SpyCatcher construct that still binds efficiently to SpyTag.	2014
SpyLigase 2	SpyTag	AHIVMVDAYKPTK	Rationally engineered system for ligating two peptides.	2014
	KTag	ATHIKFSKRD
SnoopCatcher	SnoopTag	KLGDIEFIKVNK	Orthogonal technology to SpyCatcher.	2016
SpyCatcher002	SpyTag002	VPTIVMVDAYKRYK	Improved SpyCatcher-SpyTag system with faster reaction rate.	2017
SnoopLigase 2	SnoopTagJr	KLGSIEFIKVNK	Rationally engineered system for ligating two peptides.	2018
	DogTag	DIPATYEFTDGKHYITNEPIPPK
SpyDock	SpyTag002	VPTIVMVDAYKRYK	Protein affinity purification system (Spy&Go) based on SpyCatcher.