Synthesis AEPZ-CBA
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synthesis of reducible hyperbranched poly(amidoamine) (RHB)
Michael addition copolymerization of half molar ratio of a triamine AEPZ-to-bisacrylamide monomers (CBA and MBA).
1. Weigh AEPZ (0.193 g, 1.5 mmol), add to methanol/water mixture (3.5 mL, 7/3 v/v) in a small vial.
2. Add CBA (0.260 g, 1.0 mmol) and MBA (0.308 g, 2.0 mmol) to vial.
3. React at 50 °C for 5 days, yielding a viscous solution.
4. Add small amount of 1-methylpiperazine to consume any unreacted acrylamide groups.
5. Stir for 12 h at 50 °C.
6. Add cool acetone to precipitate polymer.
7. Dry precipitate under vacuum at room temperature.